In reference to a scene in the movie, Jamie Lee Curtis and Sigourney Weaver wore the same dress to the movie's premiere.
The movie features a mini-reunion of cast members from the ABC-TV sitcom Step by Step (1991). Actors Patrick Duffy, Staci Keanan, and Christine Lakin all appear in the film in various roles. Keanan's characters name in the film, "Dana," was also her character's name in the sitcom.
When Marni Olsen learns that her brother is marrying her type-A cheerleader long dark haired high school tormentor, she is asked to please sit down by a flight attendant played by Jenna Leigh Green who portrayed the same character type on Sabrina the Teenage Witch (1996) as Libby Chessler.
At the end of the movie, the grandmother's high school rival is played by Cloris Leachman who used to trade barbs with Betty White on Mary Tyler Moore (1970) as Sue Ann Nivens and Phylis Lindstrom.
The house used by Marni's family is the same house used in Freaky Friday (2003), also starring Jamie Lee Curtis.
The Sullenger Hotels group owned by Sigourney Weaver's character Mona is named after the movie's co-producer, Betsy Sullenger.
Kristen Bell's character has the initial M.O.O. (Marni Olivia Olsen) and works for Reginald VelJohnson, whose character in ABC's Family Matters (1989) had the initials C.O.W. (Carl Otis Winslow).
Three cast members (Kristin Chenoweth, Cloris Leachman, and Meagan Holder) were members of the Gamma Phi Beta sorority.