When Diaz says to Mann, 'What is this high school? Of course, we slept together. We're adults!' This is a nod to 'John Tucker Must Die' which has a very similar plot concept.
The part of Dana, the transvestite who makes out with Nikolai Coster Waldau is played by director Nick Cassavetes long-time assistant, Colin Bannon.
Originally received an R rating for the use of the word "vagina" but after a petition and without any edits to the movie, the rating was reduced to PG-13.